Anthralin

Also indexed as: Anthraderm, Anthraforte®, Anthranol®, Anthrascalp®, Dithranol, Drithocreme®, Micanol® Cream, Psorin® Ointment

Anthralin is a drug applied only to affected skin areas to treat psoriasis.

Summary of Interactions with Vitamins, Herbs, and Foods
In some cases, an herb or supplement may appear in more than one category, which may seem contradictory. For clarification, read the full article for details about the summarized interactions.

Beneficial May be Beneficial: Side effect reduction/prevention—Taking these supplements may help reduce the likelihood and/or severity of a potential side effect caused by the medication.

Vitamin E (topical)

Depletion or interference

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Dietary Supplements

Vitamin E
Anthralin can cause inflammation of the skin. A preliminary study found that topical use of vitamin E was able to protect against this side effect.1 This report used a tocopherol form of the vitamin rather than tocopheryl. This makes sense, as there is no conclusive proof that the tocopheryl forms (which require an enzyme to split vitamin E from the fatty acid to which it is attached) have any activity on the skin.

References

1. Finnen MJ, Lawrence CM, Shuster S. Inhibition of dithranol inflammation by free-radical scavengers. Lancet 1984;ii:1129–30.