5HTP or 5- Hydroxytryptophan is a chemical derivative of the protein element, L-tryptophan. Holland & Barrett source 5-HTP supplements from the seeds of an African plant named Griffonia simplicifolia.

What is 5HTP?

5HTP is an organic substance that originates from a medicinal African plant. It also comprises the nutrient antecedent to serotonin (5-HT), a neurotransmitter, which means that 5HTP transforms into serotonin in the brain.

5HTP has been used as a recommended remedy for many conditions, including the treatment of headaches, depression and psychiatric illnesses.

Serotonin is an important neurotransmitter for the body, as it supports the functioning of various bodily and mental processes including sleep, appetite, memory, mood, muscle contraction, learning, cardiovascular performance and temperature control.

5HTP Benefits

Research has shown 5HTP to help those who suffer from cerebellar ataxia: a condition that causes difficulty in standing or walking and inept muscle movement. Research is also proposing that 5HTP may reduce alcohol withdrawal symptoms, while many studies have suggested that it may support the treatment of depression.

Moreover, 5HTP supplements have been recommended by doctors as an alternative to serotonin supplements, as 5HTP has the capacity to access the brain from the bloodstream unlike serotonin. This enables an increase of serotonin levels and a decrease in hunger cravings, as the body feels satiated more quickly.


The 5HTP range that Holland & Barrett offers includes tablets and capsules. Our products are:

Holland & Barrett are a dedicated supplier of high quality health products, supplements and foods to help support and maintain your health and wellbeing. You can browse through our wide choice of products now to find something that suits you.

Show more