Creatine magnesium chelate (MgCr-C) is a type of creatine that’s bound with
magnesium, which
suppliers claim can improve muscle protein synthesis.
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Although research remains limited, some evidence supports the effectiveness and safety profile
of creatine magnesium chelate.24
During a small double-blind clinical trial of 31 weight-trained men in 2004, researchers
evaluated the effects of creatine monohydrate, creatine magnesium chelate and a placebo. But,
while both the creatine monohydrate and creatine magnesium chelate groups showed improved
performance over the placebo group, there was no noticeable difference between the two types
of creatine.24
That said, a more recent (but still small) study published in 2020 found that 16 weeks of creatine
magnesium chelate supplementation improved the sprint ability performance of elite football
players when compared to a placebo. Nonetheless, more research is required.25