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Creatine for strength and exercise: what you need to know

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What can creatine actually do for your workout? From performance and strength to recovery, our expert reveals what the science really says

Summary

1What does creatine do for exercise?

Creatine can increase physical performance during successive bursts of short-term, high-intensity exercise when 3g is consumed daily.

2Can creatine help build muscle?

Creatine won’t build muscle on its own, but it may support increases in lean body mass when combined with resistance training.

3Does creatine help with exercise recovery?

Creatine has been studied for exercise recovery, but we need more research to understand whether it can really help you bounce back after a workout.

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Few sports nutrition supplements have received as much attention as creatine. Popular with everyone from gym-goers and strength athletes to people simply looking to get more from their workouts, creatine is one of the most extensively researched ingredients in active nutrition.

But more interest comes with more claims – and not every potential benefit associated with creatine has the same level of scientific support. We spoke to Chandni Vadgama, Registered Associate Nutritionist at Holland & Barrett, to separate what we know from what we’re still learning about creatine, exercise and performance.

What is creatine – and what does it have to do with exercise?

Creatine is a naturally occurring compound found throughout your body, with most stored in your skeletal muscles.2 Your body can make it from amino acids including arginine, glycine and methionine, and you’ll also get some through foods such as meat and fish.2,3

So, why all the interest in sports nutrition? Inside your muscles, creatine is stored in its free form and as phosphocreatine, which plays an important role in rapidly supplying energy during exercise.2 Whenever your muscles contract, they need energy in the form of ATP.4 But your muscles only store a relatively small amount at any one time. During intense exercise, those supplies can be used quickly, so phosphocreatine acts as a rapid back-up system, helping regenerate ATP when demand suddenly increases.3 

“You can think of phosphocreatine as one of the body's rapid-response energy systems,” says Chandni. “When you're performing a short burst of intense exercise, it helps replenish ATP quickly so your muscles can continue to meet that sudden increase in energy demand.”

What does the research say about creatine and exercise?

There’s a reason creatine gets so much attention in the fitness world – it’s one of the most well-researched sports nutrition ingredients. Taking 3g daily can increase physical performance during repeated bursts of short-term, high-intensity exercise.1 Research has also investigated its effects on strength, muscle mass and other aspects of exercise and training.

And with decades of research in active adults and athletes, there’s a lot to unpack. The evidence is strongest for high-intensity exercise, while research has also explored areas including strength and resistance training.

Creatine for high-intensity exercise and physical performance

So, what does ‘short-term, high-intensity exercise’ actually mean for your workout? “Creatine can be particularly useful for exercise where you need to produce a lot of energy very quickly,” says Chandni. “Think repeated sprints or sets of resistance exercise, rather than all types of exercise.”6 This is where creatine can help increase physical performance, supporting those repeated, high-intensity efforts.1,6
 

Creatine for strength training

Creatine has also been studied alongside resistance training. A 2024 systematic review and meta-analysis found that adults under 50 who combined creatine with resistance training experienced greater improvements in upper- and lower-body strength than those undertaking resistance training with a placebo.7

A more recent review similarly found small improvements in several measures of strength and power – essentially, the ability to produce force quickly, although benefits weren’t seen across every outcome measured.8 Overall, the evidence for strength is strong, but findings are less consistent than they are for short-term, high-intensity exercise.

And creatine is only one part of the picture. “Creatine can complement a well-designed training programme, but it can’t replace progressive training, good nutrition, quality sleep or adequate recovery,” explains Chandni.
 

Creatine for muscle growth

If building muscle is your goal, you might be wondering where creatine fits in. A 2024 systematic review and meta-analysis found that adults under 50 taking creatine alongside resistance training gained approximately 1.14kg more lean body mass than those completing resistance training alone.9

Overall, the research suggests a small additional increase in lean body mass when creatine is combined with resistance training. However, lean body mass doesn’t necessarily mean new muscle tissue alone, as creatine can also increase body water.6 “Creatine doesn't build muscle in isolation,” says Chandni. “The research focuses on creatine alongside resistance training, so it's important to remember that the training itself remains fundamental to building muscle.”

Curious about the scales as well as strength? Find out more about creatine and weight gain.
 

Does creatine help with exercise recovery?

Could creatine help you bounce back after a tough workout? Research has explored its effects on muscle soreness, muscle function and markers of muscle damage, but the picture isn’t clear yet. One study found lower levels of creatine kinase (CK), a marker of muscle damage, following creatine supplementation. However, there was considerable variation between studies and limitations in the quality of the research.10

Another review found that while creatine reduced CK at one point after exercise, it didn’t improve muscle soreness, strength recovery, range of motion or signs of inflammation overall.11 In other words, changes in a marker of muscle damage don’t necessarily mean you’ll recover more quickly.

“Recovery is an interesting area of creatine research, but the evidence isn't as consistent as it is for high-intensity performance,” says Chandni. “For now, exercise recovery is better viewed as an area of ongoing research rather than an established benefit of creatine.”

What about creatine for exercise as you get older?

Female putting creatine into a sports bottle
Maintaining muscle mass and strength becomes increasingly important as we age, which has led researchers to explore whether creatine could have a role alongside resistance training in older adults. One meta-analysis found greater increases in lean tissue mass and upper- and lower-body strength when creatine was combined with resistance training compared with resistance training alone.12 However, the evidence isn’t conclusive.
So, while the findings are promising, we need more high-quality studies before we can fully understand the role creatine might play in healthy ageing.

Does creatine work differently in men and women?

Here, there’s still a sizeable gap in the research as historically, much of the evidence on creatine has come from studies involving men. As a result, we know less about the effects of creatine for women. A 2025 review of 27 studies in physically active women found mixed results for outcomes including strength, power and anaerobic performance. Importantly, most studies didn’t adequately account for considerations specific to female athletes, making it harder to draw firm conclusions.14

Similarly, a 2024 meta-analysis found significant strength benefits in the predominantly male evidence base but not among female participants. However, only two of the 23 included studies involved women exclusively, so the female-specific evidence remains limited.7

“Women remain underrepresented in creatine research, so we can't assume that a lack of significant findings means creatine doesn't have an effect,” says Chandni. “We need more high-quality research involving women before we can confidently determine whether responses differ between sexes.”

What foods contain creatine?

Your body can make creatine itself, but you’ll also get some through your diet. Creatine is found primarily in animal derived foods, particularly meat and fish.2

“Creatine isn't something you need to obtain entirely through food because your body can make it itself,” explains Chandni. “For people who eat meat and fish, these foods provide an additional source alongside the creatine produced naturally by the body.”

What about vegetarians and vegans?

As dietary creatine comes predominantly from animal-derived foods, people following vegetarian and vegan diets typically consume much less than those who eat meat and fish. Research suggests that vegetarians tend to have lower muscle creatine stores than omnivores.15 However, this doesn’t automatically mean you need to take a supplement, as your body can make creatine itself.

Interestingly, a systematic review found that creatine supplementation increased muscle creatine levels in vegetarians, sometimes to a greater extent than in omnivores.16 However, it’s not yet clear whether this means vegetarians experience greater benefits from creatine for exercise performance, and limitations in the available research make it difficult to draw firm conclusions.

If you regularly do short bursts of high-intensity exercise and are considering creatine supplementation, check with a healthcare professional that it’s suitable for you.

Creatine and exercise FAQs

What does creatine do?

Creatine helps your muscles rapidly regenerate ATP – the energy they need to contract. This becomes particularly important during short bursts of high-intensity exercise, such as sprinting or resistance training. Consuming 3g of creatine daily can increase physical performance during successive bursts of short-term, high-intensity exercise.1 Thinking about giving creatine a try? Find out whether you should take creatine, as our experts break down the benefits, how to take it and potential side effects.
 

Is creatine safe?

Creatine monohydrate has been extensively studied and is generally considered well tolerated in healthy adults.18 Anyone with an existing medical condition, taking medication or who is pregnant or breastfeeding should speak to a healthcare professional before taking creatine.
 

Does creatine make you gain weight?

It can – but this doesn't necessarily mean gaining body fat. Creatine can cause some initial weight gain because it increases the amount of water stored within your muscles.6 Over time, taking creatine alongside resistance training may also support greater gains in lean body mass.9
 

When should you take creatine?

There’s no need to obsess over timing. There isn't currently strong evidence that creatine has to be taken at a particular time of day. Rather than focusing on a narrow pre- or post-workout window, consistent intake is more important because creatine works by increasing muscle creatine stores over time. Morning or night? Before or after your workout? Our guide to when to take creatine takes a closer look at the research.
 

The final say

There’s a reason creatine gets so much attention in sports nutrition. It’s one of the most extensively researched ingredients in the space, with the strongest evidence showing that 3g per day can increase physical performance during successive bursts of short-term, high-intensity exercise.1

Just don’t expect your creatine tub to do all the heavy lifting. Training, balanced nutrition, quality sleep and recovery still matter most – think of creatine as another tool in your kit rather than a shortcut to your goals.

Want to explore creatine beyond exercise? Find out what the science says about creatine and brain health. Or, if you’re considering a supplement, take a look at our top creatine supplements to try.
Disclaimer – This article provides informational advice and is not a substitute for medical care. Working with experts for accuracy, we take great care to ensure the information is up-to-date and relevant. However, you should always consult your GP or healthcare professional before using supplements or alternative products, particularly if you have medical conditions or are under supervision.

Sources

1. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). Scientific opinion on the substantiation of health claims related to creatine and increase in physical performance during short-term, high intensity, repeated exercise bouts, increase in endurance capacity, and increase in endurance performance pursuant to Article 13(1) of Regulation (EC) No 1924/2006. EFSA J. 2011;9(7):2303. Available from: https://efsa.onlinelibrary.wiley.com/doi/10.2903/j.efsa.2011.2303
2. Kreider RB, Stout JR. Creatine in health and disease. Nutrients. 2021 Jan 29;13(2):447. Available from: https://www.mdpi.com/2072-6643/13/2/447
3. da Silva RP, Nissim I, Brosnan ME, Brosnan JT. Creatine synthesis: hepatic metabolism of guanidinoacetate and creatine in the rat in vitro and in vivo. Am J Physiol Endocrinol Metab. 2009 Feb;296(2):E256-61. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC2645018/
4. Barclay CJ, Curtin NA. Advances in understanding the energetics of muscle contraction. J Biomech. 2023 Jul;156:111669. Available from: https://www.sciencedirect.com/science/article/pii/S0021929023002385
5. Fazio C, Elder CL, Harris MM. Efficacy of alternative forms of creatine supplementation on improving performance and body composition in healthy subjects: a systematic review. J Strength Cond Res. 2022 Sep 1;36(9):2663-70. Available from: https://journals.lww.com/nsca-jscr/fulltext/2022/09000/efficacy_of_alternative_forms_of_creatine.35.aspx
6. Wax B, Kerksick CM, Jagim AR, Mayo JJ, Lyons BC, Kreider RB. Creatine for exercise and sports performance, with recovery considerations for healthy populations. Nutrients. 2021 Jun 2;13(6):1915. Available from: https://www.mdpi.com/2072-6643/13/6/1915
7. Wang Z, Qiu B, Li R, Han Y, Petersen C, Liu S, et al. Effects of creatine supplementation and resistance training on muscle strength gains in adults <50 years of age: a systematic review and meta-analysis. Nutrients. 2024 Oct 28;16(21):3665. Available from: https://www.mdpi.com/2072-6643/16/21/3665
8. Kazeminasab F, Kerchi AB, Sharafifard F, Zarreh M, Forbes SC, Camera DM, et al. The effects of creatine supplementation on upper- and lower-body strength and power: a systematic review and meta-analysis. Nutrients. 2025 Aug 25;17(17):2748. Available from: https://www.mdpi.com/2072-6643/17/17/2748 
9. Desai I, Wewege MA, Jones MD, Clifford BK, Pandit A, Kaakoush NO, et al. The effect of creatine supplementation on resistance training-based changes to body composition: a systematic review and meta-analysis. J Strength Cond Res. 2024 Oct 1;38(10):1813-21. Available from: https://journals.lww.com/nsca-jscr/fulltext/2024/10000/the_effect_of_creatine_supplementation_on.19.aspx
10. Jiaming Y, Rahimi MH. Creatine supplementation effect on recovery following exercise-induced muscle damage: a systematic review and meta-analysis of randomized controlled trials. J Food Biochem. 2021 Oct;45(10):e13916. Available from: https://onlinelibrary.wiley.com/doi/10.1111/jfbc.13916 
11. Northeast B, Clifford T. The effect of creatine supplementation on markers of exercise-induced muscle damage: a systematic review and meta-analysis of human intervention trials. Int J Sport Nutr Exerc Metab. 2021 May 1;31(3):276-91. Available from: https://journals.humankinetics.com/view/journals/ijsnem/31/3/article-p276.xml
12. Chilibeck PD, Kaviani M, Candow DG, Zello GA. Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis. Open Access J Sports Med. 2017 Nov 2;8:213-26. Available from: https://www.tandfonline.com/doi/full/10.2147/OAJSM.S123529
13. Davies TW, Watson N, Pilkington JJ, McClelland TJ, Azzopardi G, Pearse RM, et al. Creatine supplementation for optimization of physical function in the patient at risk of functional disability: a systematic review and meta-analysis. JPEN J Parenter Enteral Nutr. 2024 May;48(4):389-405. Available from: https://aspenjournals.onlinelibrary.wiley.com/doi/10.1002/jpen.2607
14. Tam R, Mitchell L, Forsyth A. Does creatine supplementation enhance performance in active females? A systematic review. Nutrients. 2025 Jan 10;17(2):238. Available from: https://www.mdpi.com/2072-6643/17/2/238 
15. Blancquaert L, Baguet A, Bex T, Volkaert A, Everaert I, Delanghe J, et al. Changing to a vegetarian diet reduces the body creatine pool in omnivorous women, but appears not to affect carnitine and carnosine homeostasis: a randomised trial. Br J Nutr. 2018 Apr;119(7):759-70. Available from: https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/changing-to-a-vegetarian-diet-reduces-the-body-creatine-pool-in-omnivorous-women-but-appears-not-to-affect-carnitine-and-carnosine-homeostasis-a-randomised-trial/F1B851C15DFA5F52D2033BA24A2BD70D
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