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Fatigue fighters: our top products to support your energy

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Yawning in meetings? Don’t reach for another coffee – discover our energy-supporting essentials designed to help you through the day

Our top picks

Up to 4x higher absorption

Zooki Liposomal Vitamin B12 2500mcg Strawberry 2500 mcg 30 Sachets
4.78

Zooki

Zooki Liposomal Vitamin B12 2500mcg Strawberry 2500 mcg 30 Sachets

3 For 2 Mix & Match

£49.99

4000mg fruiting bodies

Fourfive Energy & Focus Lion's Mane 4000mg 60 Capsules
4.47

fourfive

Fourfive Energy & Focus Lion's Mane 4000mg 60 Capsules

Save up to 1/2 price

£14.74

RRP £22.00

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A yawn here and there is normal – we've all had a late night or a stressful workday. But a staggering one in eight of us feel tired all the time.1 You’ve heard it all before, but getting enough sleep, staying hydrated and eating all the nutrients you need are the first steps to a livelier you. Being tired all the time could be a sign of a deficiency or something else. So, if you’ve ruled this out with your GP, keep reading. We're sharing some of our favourite energy supplements to help you stay supported...
Berocca Acerola Cherry Flavour 20 Tablets

11 vits and minerals

Berocca

£11.90

£0.60/1 tablet

Feel supported with Berocca

In need of some energy? Drop a Berocca Boost tablet into water, let it fizz and start your day with a refreshing burst of support. Each serving contains: vitamin C, B vits, minerals zinc and magnesium, plus caffeine and guarana. Vitamin B1 and B2 contribute to energy release, helping you stay supported.3 Vitamin B12 supports the normal formation of red blood cells and helps reduce tiredness and fatigue, while B5contributes to normal mental performance.4-6 Just one tablet a day can help support you when study sessions or your day feels never-ending. Plus, it’s vegan-friendly and comes in acerola cherry flavour. Just remember not to exceed 400mg of caffeine per day.
 
New Nordic Magic Magnesium Citrate 60 Gummies

Easy to absorb

New Nordic

£23.99

£0.40/1 Chewable

Citrus, smart and seriously chill

Let’s face it, gummies are a fun way to take your supplements and New Nordic are the brains behind these chewy citrus delights. Magnesium is needed for many functions in the body and one of them is helping to reduce tiredness and fatigue.7,8 But why magnesium citrate? Well, it’s said to be highly absorbable by our bodies.7,9 Just two gummies per day provide 120mg of magnesium.
 
Fourfive Energy & Focus Lion's Mane 4000mg 60 Capsules

4000mg fruiting bodies

fourfive

RRP £22.00

£14.74

£0.25/1 Capsule

B vitamins and lion's mane

Founded by rugby pros George Kruis and Dom Day, fourfive is on a mission to ‘empower the moments that matter’ and to make daily goals that bit simpler. Two of these vegan lion’s mane mushroom capsules contain 4000mg of the fruiting bodies from log-grown mushrooms. Plus, there are vitamins B12 and B6 to support psychological function and energy-yielding metabolism (turning your food into energy), as well as caffeine source guarana.10
 
Zooki Liposomal Vitamin B12 2500mcg Strawberry 2500 mcg 30 Sachets

Up to 4x higher absorption

Zooki

£49.99

£1.67/1 Sachet

Rip, sip, and get on with your day

Each Zooki sachet delivers high-strength, bioactive methylcobalamin in a naturally sweet strawberry flavour, with liposomal technology designed to support absorption. Vitamin B12 is the star here – contributing to normal energy release and helping to reduce tiredness and fatigue.12 B12 also contributes to normal nervous and immune system function.13 Vegan, sugar-free and great for life on the go, simply rip and sip a sachet.
 
Fighting Fatigue Energy, Iron & Vitamin B12 Support 120 Tablets

Vitamin B complex

Prime Fifty

£32.00

£0.27/1 Item

Over 50? Meet your everyday energy support

Fighting Fatigue has been specially formulated for the over-50s, with a tailored blend of essential vitamins and minerals to support your everyday energy needs. It includes B vitamins, iron, vitamins C, D and E, co-enzyme Q10, zinc and magnesium, with vitamins B1, B2, B3, B6, B12 and folic acid to contribute to the reduction of tiredness and fatigue. Each multivitamin has been designed with the nutritional needs of over-50s in mind.
 

Vitamins for fatigue FAQs

What vitamins help with tiredness?

Several vitamins have recognised roles in energy metabolism and the reduction of tiredness and fatigue. Vitamins B2, B3, B5, B6, B12 and C, as well as folate, contribute to the reduction of tiredness and fatigue.10 Vitamin B1 (thiamine) also contributes to normal energy-yielding metabolism.17 Low levels of certain nutrients can be associated with tiredness. For example, vitamin B12 or folate deficiency can lead to anaemia, which may cause symptoms including tiredness and weakness. It's important to remember that taking extra vitamins won’t necessarily give you more energy if you’re already getting enough of them. If tiredness persists, it’s worth speaking to a healthcare professional to identify the underlying cause.10
 

What vitamins should you take daily?

Most people can get the vitamins and minerals they need from a varied, balanced diet, so taking a daily supplement isn't necessary for everyone.18 Important vitamins include vitamins A, C, D, E, K and the B vitamins.18 Some adults over 50 may experience reduced absorption of vitamin B12 from food and vitamin D.18 If you’re considering a supplement, it’s best to speak with a doctor or dietitian, as taking too much of certain vitamins can be harmful.
 

Does vitamin D give you energy?

Vitamin D doesn’t directly give you energy. Instead, it has several important roles in the body, including contributing to the maintenance of normal muscle function and the normal function of the immune system.19
 

The final say

Still awake? Also check out this round-up of our best energy drinks. Remember, these picks are all about supporting an already healthy lifestyle. If your tiredness isn’t getting better with plenty of sleep and a balanced diet, or you’re finding it difficult to live your usual life, speak to a GP. Curious about what good-quality rest means for you? Well, did you know your personality could play a part? We speak to psychologist Dr Ravi Gill for expert tips and activities that will help you unlock your deepest chill state.
Disclaimer – This article provides informational advice and is not a substitute for medical care. Curated by experts for accuracy, we take great care to ensure the information is up-to-date and relevant. However, you should always consult your GP or healthcare professional before using supplements or alternative products, particularly if you have medical conditions or are under supervision.

Sources

1. YouGov. One in eight Britons feel tired all the time [Internet]. YouGov [cited 2025 Apr 28]. Available from: https://yougov.co.uk/society/articles/40047-one-eight-britons-feel-tired-all-time
2. Zhang M, Han W, Hu S, Xu H. Methylcobalamin: A Potential Vitamin of Pain Killer. Neural Plasticity [Internet]. 2013;2013:1–6. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888748/pdf/NP2013-424651.pdf/?tool=EBI
3. NHS. B Vitamins and Folic Acid - Vitamins and Minerals [Internet]. NHS. 2020. Available from: https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-b/
4. European Commission. Characteristics [Internet]. European Commission [cited 2025 Apr 28]. Available from: https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6395
5. European Commission. Characteristics [Internet]. European Commission [cited 2025 Apr 28]. Available from: https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6428
6. European Commission. Characteristics [Internet]. European Commission [cited 2025 Apr 28]. Available from: https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6435
7. National Institutes of Health. Magnesium: Health professional fact sheet. National Institutes of Health [cited 2025 Apr 28]. Available from: https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
8. European Commission. Characteristics [Internet]. European Commission [cited 2025 Apr 28]. Available from: https://ec.europa.eu/food/food-feed-portal/screen/health-claims/eu-register/details/POL-HC-6401
9. Walker AF, Marakis G, Christie S, Byng M. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnes Res [Internet]. 2003 Sep [cited 2025 Apr 28]; 16(3): 183-91. Available from: https://pubmed.ncbi.nlm.nih.gov/14596323/
10. Tardy AL, Pouteau E, Marquez D, Yilmaz C, Scholey A. Vitamins and minerals for energy, fatigue and cognition: A narrative review of the biochemical and clinical evidence. Nutrients [Internet]. 2020 Jan 16;12(1):228. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC7019700/
11. Burns BC, Belani J D, Wittorf HN, Eugen Brailoiu, Brailoiu GC. Choline—An Essential Nutrient with Health Benefits and a Signaling Molecule. International Journal of Molecular Sciences [Internet]. 2025 July 24 [cited 2026 Aug 21];26(15):7159–9. Available from: https://www.mdpi.com/1422-0067/26/15/7159
12. National Institutes of Health. Office of Dietary Supplements - Vitamin B12 [Internet]. Nih.gov. National Institutes of Health; 2024 [cited 2026 Aug 21]. Available from: https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/
13. Batista KS, Cintra VM, Lucena PAF, Manhães-de-Castro R, Toscano AE, Costa LP, et al. The role of vitamin B12 in viral infections: a comprehensive review of its relationship with the muscle–gut–brain axis and implications for SARS-CoV-2 infection. Nutrition Reviews. 2021 Nov 13;80(3).
14. Fischer JAJ, Cherian AM, Bone JN, Karakochuk C D. The effects of oral ferrous bisglycinate supplementation on hemoglobin and ferritin concentrations in adults and children: a systematic review and meta-analysis of randomized controlled trials. Nutrition Reviews. 2023 Feb 2;81(8). 
15. Lynch S, Cook J. Interaction of Vitamin C and Iron [Internet]. Annals of the New York Academy of Sciences. 1980 [cited 2026 Aug 21]. Available from: https://pubmed.ncbi.nlm.nih.gov/6940487/
16. National Institutes of Health. Iron: Fact Sheet for Health Professionals [Internet]. National Institutes of Health. 2024 [cited 2026 Aug 21]. Available from: https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/
17. Mrowicka M, Mrowicki J, Dragan G, Majsterek I. The Importance of Thiamine (vitamin B1) in humans. Bioscience Reports. 2023 June 30;43(10).
18. National Institute on Aging. Vitamins and Minerals for Older Adults [Internet]. National Institute on Aging. 2021 [cited 2026 Aug 21]. Available from: https://www.nia.nih.gov/health/vitamins-and-supplements/vitamins-and-minerals-older-adults
19. Di Molfetta IV, Bordoni L, Gabbianelli R, Sagratini G, Alessandroni L. Vitamin D and Its Role on the Fatigue Mitigation: A Narrative Review. Nutrients [Internet]. 2024 Jan 1 [cited 2026 Aug 21];16(2):221. Available from: https://www.mdpi.com/2072-6643/16/2/221
 
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